Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.39 |
| ▸ | PPARG | P37231 | 10/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478715 | 1.00 | PPARA (0.39) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| SCHEMBL5479203 | 1.00 | PPARA (0.39) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| SCHEMBL22644024 | 0.85 | PPARA (0.43) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| SCHEMBL10877675 | 0.82 | PPARA (0.42) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| SCHEMBL5481863 | 0.78 | SLC6A4 (0.56) | PPARAPPARGSLC6A4SIGMAR1 | |
| SCHEMBL5481862 | 0.78 | SLC6A4 (0.56) | PPARAPPARGSLC6A4SIGMAR1 | |
| SCHEMBL5481857 | 0.78 | SLC6A4 (0.56) | PPARAPPARGSLC6A4SIGMAR1 | |
| SCHEMBL8887015 | 0.78 | PPARA (0.41) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| SCHEMBL13124568 | 0.77 | PPARA (0.43) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL5474756 | 0.77 | SLC6A4 (0.55) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901466-B1 | BIPHENYLSULFONAMIDE MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0901466-A1 | BIPHENYLSULFONAMIDE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-03-17 | — | — | EP | disclosed |
| US-5756545-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | WARNER-LAMBERT COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1997044315-A1 | BIPHENYLSULFONAMIDE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1997-11-27 | — | — | WO | disclosed |