Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.39 |
| ▸ | PPARG | P37231 | 10/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409107 | 1.00 | PPARA (0.39) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| SCHEMBL5478715 | 1.00 | PPARA (0.39) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| SCHEMBL22644024 | 0.85 | PPARA (0.43) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| SCHEMBL10877675 | 0.82 | PPARA (0.42) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| SCHEMBL5481863 | 0.78 | SLC6A4 (0.56) | PPARAPPARGSLC6A4SIGMAR1 | |
| SCHEMBL5481862 | 0.78 | SLC6A4 (0.56) | PPARAPPARGSLC6A4SIGMAR1 | |
| SCHEMBL5481857 | 0.78 | SLC6A4 (0.56) | PPARAPPARGSLC6A4SIGMAR1 | |
| SCHEMBL8887015 | 0.78 | PPARA (0.41) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| SCHEMBL13124568 | 0.77 | PPARA (0.43) | PPARAPPARGSLC6A4L3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL5474756 | 0.77 | SLC6A4 (0.55) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072859-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072859-A1 | Pharmaceutical compounds | ADRB3, HTR3C, SLC6A2 | PPARA 4023/4885PPARG 3659/4885SLC6A4 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.