SCHEMBL8887015

SCHEMBL8887015

[CH2]C(CCC)Oc1ccc(Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 12/20 0.41
PPARG P37231 11/20 0.41
SLC6A4 P31645 1/20 0.41
POLB P06746 1/20 0.38
SIGMAR1 Q99720 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
P2RX3 P56373 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8923714 0.89 PPARA (0.42) PPARAPPARGSLC6A4POLBSIGMAR1
SCHEMBL8995789 0.84 PPARA (0.40) PPARAPPARGSLC6A4POLBSIGMAR1
SCHEMBL8923941 0.81 SLC6A4 (0.41) PPARAPPARGSLC6A4L3MBTL1
SCHEMBL8925965 0.81 DRD2 (0.39)
SCHEMBL13124568 0.80 PPARA (0.43) PPARAPPARGSLC6A4POLBSIGMAR1
SCHEMBL7350372 0.80 SLC6A4 (0.41) PPARAPPARGSLC6A4POLB
SCHEMBL8887237 0.79 SLC6A4 (0.47) SLC6A4L3MBTL1
SCHEMBL5479203 0.78 PPARA (0.39) PPARAPPARGSLC6A4POLBSIGMAR1
SCHEMBL7409107 0.78 PPARA (0.39) PPARAPPARGSLC6A4POLBSIGMAR1
SCHEMBL5478715 0.78 PPARA (0.39) PPARAPPARGSLC6A4POLBSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691340-A CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS ADIR ET COMPAGNIE (FR) 1997-11-25 US disclosed
US-5677263-A CONTROLLING UNWANTED GRASSES BASF AKTIENGESELLSCHAFT (DE) 1997-10-14 US disclosed
US-5523462-A HERBICIDES; PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1996-06-04 US disclosed