Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667120 | 0.78 | CYP2C19 (0.45) | GAALMNA | |
| SCHEMBL7409138 | 0.76 | GAA (0.34) | MEN1POLBKMT2AGAALMNA | |
| SCHEMBL23042677 | 0.71 | ALDH1A1 (0.42) | MEN1POLBKMT2AGAALMNA | |
| SCHEMBL8629131 | 0.71 | — | — | |
| SCHEMBL28262852 | 0.70 | CYP2C19 (0.43) | MEN1POLBKMT2AGAALMNA | |
| SCHEMBL7517972 | 0.69 | MEN1 (0.40) | MEN1POLBKMT2ALMNA | |
| SCHEMBL28061397 | 0.69 | DPP4 (0.37) | — | |
| SCHEMBL8625726 | 0.68 | CETP (0.33) | — | |
| SCHEMBL12584672 | 0.67 | ALDH1A1 (0.35) | MEN1POLBKMT2ALMNA | |
| SCHEMBL8630537 | 0.66 | CETP (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047599-A1 | SUCCINAMIDE DERIVATIVES USEFUL AS TNF- AND/OR MMP INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-18 | — | — | WO | disclosed |