Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.65 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 9/20 | 0.45 |
| ▸ | HTR1D | P28221 | 7/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415658 | 0.85 | HTR1F (0.63) | HTR1FBAZ2BHTR1BHTR1DHTR1A | |
| SCHEMBL7656895 | 0.85 | HTR1F (0.66) | HTR1FBAZ2BHTR1BHTR1DHTR1A | |
| SCHEMBL7408960 | 0.84 | HTR1F (0.59) | HTR1FHTR1BHTR1DHTR1AKMT2A | |
| SCHEMBL11334169 | 0.84 | HTR1F (0.74) | HTR1FBAZ2BHTR1BHTR1DHTR1A | |
| SCHEMBL7403681 | 0.83 | HTR1F (0.56) | HTR1FBAZ2BHTR1BHTR1DKMT2A | |
| SCHEMBL7666163 | 0.83 | HTR1F (0.71) | HTR1FBAZ2BHTR1BHTR1DHTR1A | |
| SCHEMBL7663867 | 0.83 | HTR1F (0.71) | HTR1FHTR1BHTR1DHTR1AKMT2A | |
| SCHEMBL7407071 | 0.83 | HTR1F (0.71) | HTR1FBAZ2BHTR1BHTR1DHTR1A | |
| SCHEMBL12129620 | 0.82 | HTR1F (0.56) | HTR1FHTR1BHTR1DHTR1AKMT2A | |
| Bromide SCHEMBL7666990 | 0.82 | HTR1F (0.70) | HTR1FHTR1BHTR1DHTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |