Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 7/20 | 0.42 |
| ▸ | HTR1B | P28222 | 7/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7543375 | 0.95 | HTR1F (0.63) | HTR1FKMT2AMEN1HTR1DHTR1B | |
| SCHEMBL8647158 | 0.89 | HTR1F (0.52) | HTR1FKMT2AMEN1HTR1DHTR1B | |
| SCHEMBL7409147 | 0.85 | HTR1F (0.65) | HTR1FKMT2AMEN1HTR1DHTR1B | |
| SCHEMBL2323086 | 0.85 | HTR1F (0.48) | HTR1FKMT2AMEN1HTR1DHTR1B | |
| Oxalic Acid SCHEMBL7541311 | 0.85 | HTR1F (0.52) | HTR1FKMT2AMEN1HTR1DHTR1B | |
| SCHEMBL7026047 | 0.84 | HTR1F (0.52) | HTR1FKMT2AMEN1HTR1DHTR1B | |
| SCHEMBL11334169 | 0.83 | HTR1F (0.74) | HTR1FKMT2AMEN1HTR1DHTR1B | |
| SCHEMBL2301469 | 0.82 | HTR1B (0.61) | HTR1FKMT2AMEN1HTR1DHTR1B | |
| SCHEMBL7031093 | 0.82 | HTR1B (0.61) | HTR1FKMT2AMEN1HTR1DHTR1B | |
| SCHEMBL980209 | 0.82 | HTR1B (0.61) | HTR1FKMT2AMEN1HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603432-B1 | Tetrahydrocarbazole derivatives for the manufacture of a medicament for the treatment of a disease where a 5-HT1-like agonist is indicated | SMITHKLINE BEECHAM PLC (GB) | 1998-10-21 | — | — | EP | claimed |
| EP-0591280-B1 | USE OF TETRAHYDROCARBAZOLE DERIVATIVES AS 5HT1-RECEPTOR AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-09-09 | — | — | EP | claimed |
| EP-0603432-A1 | Tetrahydrocarbazole derivatives for the manufacture of a medicament for the treatment of a disease where a 5-HT1-like agonist is indicated | SMITHKLINE BEECHAM PLC (GB) | 1994-06-29 | — | — | EP | claimed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |