Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409155 | 1.00 | CTSK (0.50) | CTSKITGB3ITGA2BF2PRSS1 | |
| SCHEMBL8254962 | 0.89 | CTSK (0.50) | CTSKITGB3ITGA2BF2PRSS1 | |
| SCHEMBL13766136 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BF2PRSS1ACE | |
| SCHEMBL5916349 | 0.85 | CMA1 (0.43) | ITGB3ITGA2BF2PRSS1ACE | |
| SCHEMBL9510956 | 0.84 | KMT2A (0.52) | CTSKF2PRSS1CTSSACE | |
| SCHEMBL12463881 | 0.84 | CMA1 (0.49) | ITGB3ITGA2BF2PRSS1ACE | |
| SCHEMBL6913217 | 0.83 | CMA1 (0.43) | ITGB3ITGA2BF2PRSS1ACE | |
| SCHEMBL6887770 | 0.83 | CMA1 (0.43) | ITGB3ITGA2BF2PRSS1ACE | |
| SCHEMBL13667609 | 0.83 | ACE (0.55) | CTSKITGB3ITGA2BF2PRSS1 | |
| SCHEMBL12784960 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BF2PRSS1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244884-A | Tripeptide | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-09-14 | — | — | US | disclosed |