SCHEMBL7409160

SCHEMBL7409160

CCc1c(C)ccc(C(=O)O)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.41
GABRD O14764 2/20 0.41
GABRA1 P14867 2/20 0.41
GABRB1 P18505 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRA3 P34903 2/20 0.41
GABRA2 P47869 2/20 0.41
GABRB2 P47870 2/20 0.41
GABRA4 P48169 2/20 0.41
GABRE P78334 2/20 0.41
GABRA6 Q16445 2/20 0.41
GABRG1 Q8N1C3 2/20 0.41
GABRG3 Q99928 2/20 0.41
GABRQ Q9UN88 2/20 0.41
HAAO P46952 1/20 0.40
CYP1A2 P05177 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10901788 0.88 GABRP (0.43) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28733643 0.86 GABRP (0.42) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8226800 0.85 GABRP (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7072975 0.84 GABRP (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28733526 0.84 GABRP (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL13199183 0.84 PTGER4 (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL3000590 0.82 GABRP (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18280372 0.82 HAAO (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28670020 0.82 CSNK2A1 (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2581660 0.82 KDM4E (0.50) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315728-A Imidazole ionic liquid and application thereof in alcoholysis polymerization of 2, 5-furandicarboxylic acid ester 中国科学院大连化学物理研究所 2022-04-12 CN claimed
CN-112384489-A Method for producing organic compound 尤尼吉可株式会社 2021-02-19 CN disclosed
US-6191171-B1 ANTAGONISTS, USEFUL IN INHIBITION OR PREVENTION OF CELL ADHESION AND CELL-ADHESION MEDIATED PATHOLOGIES; FOR DRUGS FOR TREATMENT OF ASTHMA, ALLERGIES, INFLAMMATION, MULTIPLE SCLEROSIS, AND OTHER INFLAMMATORY AND AUTOIMMUNE DISORDERS MERCK & CO., INC. 2001-02-20 US disclosed
WO-1999026923-A1 PARA-AMINOMETHYLARYL CARBOXAMIDE DERIVATIVES MERCK & CO., INC. (US) 1999-06-03 WO disclosed