SCHEMBL2581660

SCHEMBL2581660

CCc1c(C)ccc(C(=O)O)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
SELL P14151 1/20 0.45
SELP P16109 1/20 0.45
HMGB1 P09429 1/20 0.42
CXCL12 P48061 1/20 0.42
GRM1 Q13255 1/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MCL1 Q07820 1/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8374984 0.86 SELL (0.50) KDM4EALDH1A1HPGDHSD17B10SELL
SCHEMBL28512376 0.85 LDHA (0.47) KDM4EALDH1A1HPGDHSD17B10SELL
SCHEMBL8029592 0.85 ALDH1A1 (0.50) KDM4EALDH1A1HPGDHSD17B10SELL
SCHEMBL28733643 0.84 GABRP (0.42) KDM4EALDH1A1HPGDHSD17B10HMGB1
SCHEMBL9874859 0.82 SELL (0.57) KDM4EALDH1A1HPGDHSD17B10SELL
SCHEMBL7409160 0.82 GABRP (0.41) KDM4EALDH1A1HPGDHSD17B10MCL1
SCHEMBL31336021 0.82 SELL (0.57) KDM4EALDH1A1HPGDHSD17B10SELL
SCHEMBL6683046 0.82 SELL (0.47) KDM4EALDH1A1HPGDHSD17B10SELL
SCHEMBL3000590 0.81 GABRP (0.40) KDM4EALDH1A1HPGDHSD17B10HMGB1
SCHEMBL9827291 0.79 TSHR (0.41) KDM4EALDH1A1HPGDHSD17B10MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0876325-B1 METHOD FOR PREPARING SCENTING COMPOSITIONS AND SCENTED PRODUCTS, AND RESULTING PRODUCTS RHODIA CHIMIE SA (FR) 2002-01-09 EP claimed
CN-114560837-A Chromone compound and preparation method and application thereof 五邑大学 2022-05-31 CN disclosed
CN-114341145-A Chemical compound 博拉公司 2022-04-12 CN disclosed
EP-2566455-B1 TOPICAL COMPOSITION AND USE THEREOF FOR THE PROPHYLAXIS AND THE TREATMENT OF DEFECTS CONNECTED TO INFLAMMATORY DERMOPATHIES SKINIUS S R L (IT) 2018-09-12 EP disclosed
US-8821904-B2 Topical composition and use thereof for the prophylaxis and the treatment of defects connected to inflammatory dermopathies SKINIUS S.R.L. (IT) 2014-09-02 US disclosed
US-20130101686-A1 Topical Composition and Use Thereof for the Prophylaxis and the Treatment of Defects Connected to Inflammatory Dermopathies SKINIUS S.R.L. (IT) 2013-04-25 US disclosed
EP-2566455-A1 TOPICAL COMPOSITION AND USE THEREOF FOR THE PROPHYLAXIS AND THE TREATMENT OF DEFECTS CONNECTED TO INFLAMMATORY DERMOPATHIES Skinius S.R.L. (IT) 2013-03-13 EP disclosed
EP-2387990-A1 Topical composition and use thereof for the prophylaxis and the treatment of defects connected to inflammatory dermopathies Skinius S.R.L. (IT) 2011-11-23 EP disclosed
WO-2011138364-A1 TOPICAL COMPOSITION AND USE THEREOF FOR THE PROPHYLAXIS AND THE TREATMENT OF DEFECTS CONNECTED TO INFLAMMATORY DERMOPATHIES SKINIUS S.R.L. (IT) 2011-11-10 WO disclosed