Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GCK | P35557 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397071 | 0.89 | TSHR (0.52) | TSHRGAACYP2C19ALDH1A1KDM4E | |
| SCHEMBL7365043 | 0.74 | KMT2A (0.52) | TSHRGAACYP2C19ALDH1A1KDM4E | |
| SCHEMBL735675 | 0.71 | TSHR (0.81) | TSHRGAACYP2C19ALDH1A1KMT2A | |
| SCHEMBL18711922 | 0.68 | TSHR (0.70) | TSHRGAACYP2C19ALDH1A1KDM4E | |
| N-Benzylmethylamine SCHEMBL29834172 | 0.68 | LMNA (0.53) | ALDH1A1KDM4EKMT2APKMMAPT | |
| SCHEMBL10077130 | 0.67 | L3MBTL1 (0.71) | TSHRGAACYP2C19ALDH1A1KDM4E | |
| SCHEMBL12067603 | 0.67 | TSHR (0.63) | TSHRGAACYP2C19ALDH1A1KDM4E | |
| SCHEMBL18702279 | 0.65 | TSHR (0.65) | TSHRGAACYP2C19ALDH1A1KDM4E | |
| SCHEMBL6738518 | 0.65 | TSHR (0.96) | TSHRGAACYP2C19ALDH1A1KDM4E | |
| SCHEMBL12384638 | 0.65 | NPSR1 (0.60) | TSHRGAACYP2C19ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211183-B1 | PIPERAZINE DERIVATIVE ANTICOAGULANTS; ANTIISCHEMIC AGENTS; CARDIOVASCULAR DISORDERS | COR THERAPEUTICS, INC. | 2001-04-03 | — | — | US | disclosed |
| EP-0975625-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046591-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |