Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.61 |
| ▸ | CTSL | P07711 | 7/20 | 0.61 |
| ▸ | CTSB | P07858 | 6/20 | 0.61 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5934862 | 1.00 | CTSK (0.61) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6682329 | 1.00 | CTSK (0.61) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5934876 | 0.93 | CTSK (0.60) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6684776 | 0.93 | CTSK (0.60) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL7371431 | 0.92 | CTSK (0.56) | CTSKCTSLCTSBCTSS | |
| SCHEMBL7164311 | 0.92 | CTSK (0.56) | CTSKCTSLCTSBCTSS | |
| SCHEMBL7163315 | 0.92 | CTSK (0.60) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5935088 | 0.92 | CTSK (0.58) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL7411725 | 0.92 | CTSK (0.60) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6685164 | 0.92 | CTSK (0.58) | CTSKCTSLCTSBCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |