Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.49 |
| ▸ | TDO2 | P48775 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412490 | 0.89 | TACR1 (0.46) | PNMTIDO1TDO2TACR1AKR1C3 | |
| SCHEMBL2086020 | 0.81 | IDO1 (0.56) | IDO1TDO2L3MBTL1 | |
| SCHEMBL21495213 | 0.81 | IDO1 (0.56) | IDO1TDO2L3MBTL1 | |
| SCHEMBL9311628 | 0.75 | PNMT (0.61) | PNMTIDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL14387383 | 0.75 | SLC6A2 (0.48) | IDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL3914167 | 0.74 | PNMT (0.59) | PNMTIDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL6000918 | 0.71 | PNMT (0.60) | PNMTIDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL12086050 | 0.71 | IDO1 (0.53) | PNMTIDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL24779826 | 0.71 | PNMT (0.65) | PNMTIDO1TDO2SLC6A4ACP3 | |
| SCHEMBL4617152 | 0.71 | PNMT (0.65) | PNMTIDO1TDO2SLC6A4ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988003147-A1 | SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | disclosed |