Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | TDO2 | P48775 | 3/20 | 0.46 |
| ▸ | CTSA | P10619 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409508 | 0.89 | PNMT (0.51) | TACR1IDO1TDO2PNMTAKR1C3 | |
| SCHEMBL21495213 | 0.80 | IDO1 (0.56) | IDO1TDO2 | |
| SCHEMBL2086020 | 0.80 | IDO1 (0.56) | IDO1TDO2 | |
| SCHEMBL4743517 | 0.78 | HTR2A (0.59) | TACR1IDO1TDO2CACNA1FCACNA1D | |
| SCHEMBL14387383 | 0.71 | SLC6A2 (0.48) | IDO1TDO2CACNA1C | |
| SCHEMBL7422189 | 0.70 | KMT2A (0.43) | IDO1TDO2CACNA1C | |
| SCHEMBL6001132 | 0.68 | TAAR1 (0.50) | IDO1TDO2 | |
| SCHEMBL6993305 | 0.67 | ADRA2A (0.40) | — | |
| SCHEMBL6001484 | 0.67 | HRH1 (0.59) | IDO1TDO2 | |
| SCHEMBL17529671 | 0.67 | CA1 (0.50) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988003147-A1 | SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | disclosed |