Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.47 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411645 | 0.92 | HTR1B (0.49) | HTR1DHTR1BKMT2AMEN1BAZ2B | |
| SCHEMBL7406466 | 0.89 | KMT2A (0.50) | HTR1DHTR1BKMT2AMEN1KDR | |
| SCHEMBL7413807 | 0.88 | KMT2A (0.46) | HTR1DHTR1BKMT2AMEN1MAPT | |
| SCHEMBL7410585 | 0.87 | KMT2A (0.51) | HTR1DHTR1BKMT2AMEN1BAZ2B | |
| SCHEMBL7409022 | 0.86 | KMT2A (0.47) | HTR1DHTR1BKMT2AMEN1LMNA | |
| SCHEMBL7407819 | 0.86 | KMT2A (0.44) | HTR1DHTR1BKMT2AMEN1SIRT1 | |
| SCHEMBL12127595 | 0.86 | SIRT1 (0.51) | HTR1DHTR1BKMT2AMEN1BAZ2B | |
| SCHEMBL7413500 | 0.85 | SIRT1 (0.50) | HTR1DHTR1BKMT2AMEN1BAZ2B | |
| SCHEMBL7407777 | 0.84 | NR2E1 (0.53) | KMT2AMEN1CYP1A2CYP2D6ALOX15 | |
| Hydrochloric Acid SCHEMBL7417242 | 0.83 | NR2E1 (0.52) | KMT2AMEN1CYP1A2CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |