Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HTR1B | P28222 | 3/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | RB1 | P06400 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413807 | 0.90 | KMT2A (0.46) | KMT2AMEN1HTR1BSMN1; SMN2HTR1A | |
| SCHEMBL12127595 | 0.88 | SIRT1 (0.51) | KMT2AMEN1HTR1BSIRT1BAZ2B | |
| SCHEMBL7410108 | 0.87 | HTR1D (0.58) | KMT2AMEN1HTR1BSIRT1BAZ2B | |
| SCHEMBL7413500 | 0.87 | SIRT1 (0.50) | KMT2AMEN1HTR1BSIRT1BAZ2B | |
| SCHEMBL7407777 | 0.86 | NR2E1 (0.53) | KMT2AMEN1RB1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7417242 | 0.85 | NR2E1 (0.52) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL7406466 | 0.84 | KMT2A (0.50) | KMT2AMEN1HTR1BHTR1AHTR1D | |
| SCHEMBL7031370 | 0.84 | KMT2A (0.46) | KMT2AMEN1HTR1BSMN1; SMN2HTR1A | |
| SCHEMBL7409022 | 0.83 | KMT2A (0.47) | KMT2AMEN1HTR1BSMN1; SMN2HTR1D | |
| SCHEMBL7411645 | 0.83 | HTR1B (0.49) | KMT2AMEN1HTR1BSIRT1BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |