Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449699 | 0.83 | MLLT1 (0.38) | MAPK14LMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL7101514 | 0.74 | F2 (0.57) | HDAC6NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL7101520 | 0.74 | F2 (0.57) | HDAC6NPC1ALDH1A1MAPK1RAB9A | |
| SCHEMBL6457217 | 0.74 | F2 (0.56) | LMNAMAPTNPC1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7451035 | 0.73 | F2 (0.56) | LMNAMAPTNPC1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7448447 | 0.73 | F2 (0.56) | LMNAMAPTNPC1ALDH1A1MAPK1 | |
| SCHEMBL7450226 | 0.72 | F2 (0.49) | LMNAMAPTNPC1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7416820 | 0.71 | F2 (0.47) | LMNAMAPTNPC1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7445570 | 0.71 | F2 (0.48) | LMNAMAPTNPC1ALDH1A1MAPK1 | |
| SCHEMBL7442305 | 0.71 | F2 (0.48) | LMNAMAPTNPC1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244636-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | Boehringer Ingelheim Pharma KG (DE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047896-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | disclosed |