Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9941834 | 0.80 | KMT2A (0.57) | POLBKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL15609263 | 0.78 | KMT2A (0.71) | POLBATMKMT2AALDH1A1TSHR | |
| SCHEMBL9941840 | 0.78 | MAPT (0.67) | POLBKMT2AALDH1A1TSHRUSP2 | |
| SCHEMBL9941647 | 0.75 | ALDH1A1 (0.55) | POLBKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL15609099 | 0.75 | KMT2A (0.54) | POLBKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9941200 | 0.74 | POLB (0.59) | POLBKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9941608 | 0.74 | CYP19A1 (0.70) | KMT2AALDH1A1TSHRUSP2LMNA | |
| SCHEMBL13063891 | 0.73 | KMT2A (0.71) | POLBKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL15609891 | 0.73 | ALDH1A1 (0.73) | POLBKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9942828 | 0.73 | POLB (0.55) | POLBKMT2AALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |