Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11879591 | 0.98 | LMNA (0.75) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL77563 | 0.88 | CES1 (0.70) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL10522051 | 0.88 | ALDH1A1 (0.58) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL28999752 | 0.87 | LMNA (0.67) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL9693670 | 0.85 | CES1 (0.67) | LMNAABCC4GAATSHRPTGS1 | |
| Hydrochloric Acid SCHEMBL27690655 | 0.85 | CES1 (0.67) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL6187747 | 0.85 | LMNA (0.70) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL12550972 | 0.85 | LMNA (0.53) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL12831751 | 0.85 | LMNA (0.64) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL12923057 | 0.85 | LMNA (0.64) | LMNAABCC4GAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026923-A1 | PARA-AMINOMETHYLARYL CARBOXAMIDE DERIVATIVES | MERCK & CO., INC. (US) | 1999-06-03 | — | — | WO | claimed |
| US-7635741-B2 | Curable polyacetylenes used as dielectrics in making microelectronics such as integrated circuits | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-22 | — | — | US | disclosed |
| US-7626059-B2 | Multifunctional ethynyl substituted monomers and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-01 | — | — | US | disclosed |
| US-20090012193-A1 | Multifunctional Ethynyl Substituted Monomers and Polyarylene Compositions Therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2009-01-08 | — | — | US | disclosed |
| US-20070037894-A1 | Multifunctional menomers and polyarylene compsotions therefrom | HAHNFELD JERRY L | 2007-02-15 | — | — | US | disclosed |
| WO-1999026923-A1 | PARA-AMINOMETHYLARYL CARBOXAMIDE DERIVATIVES | MERCK & CO., INC. (US) | 1999-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012193-A1 | Multifunctional Ethynyl Substituted Monomers and Polyarylene Compositions Therefrom | WEE2, WASF2, WEE1 | LMNA 347/4885ABCC4 3344/4885GAA 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.