Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 6/20 | 0.42 |
| ▸ | HTR1D | P28221 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651487 | 0.84 | HTR1F (0.78) | HTR1FMAPTLMNAKMT2ATP53 | |
| SCHEMBL7658032 | 0.83 | HTR1F (0.53) | HTR1FHTR6MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7659662 | 0.82 | HTR1F (0.52) | HTR1FHTR6MAPTLMNAKMT2A | |
| SCHEMBL7403681 | 0.81 | HTR1F (0.56) | HTR1FLMNAKMT2AHTR1BHTR1D | |
| SCHEMBL7410109 | 0.80 | HTR1F (0.55) | HTR1FHTR6KMT2AMEN1HTR1B | |
| SCHEMBL7417626 | 0.80 | HTR1F (0.55) | HTR1FHTR6LMNAKMT2ATP53 | |
| SCHEMBL6964061 | 0.80 | HTR1F (0.55) | HTR1FHTR6MAPTKMT2AHTR1B | |
| SCHEMBL7407128 | 0.80 | HTR1F (0.67) | HTR1FHTR6KMT2AHTR1BHTR1D | |
| SCHEMBL6963427 | 0.80 | HTR1F (0.58) | HTR1FKMT2AMEN1HTR1BHTR1D | |
| SCHEMBL7412227 | 0.80 | MAPT (0.60) | HTR1FMAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |