Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.54 |
| ▸ | ITGAV | P06756 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 3/20 | 0.45 |
| ▸ | CTRC | Q99895 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375597 | 0.91 | CA12 (0.48) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7409607 | 0.89 | ITGB3 (0.47) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7375475 | 0.88 | CA12 (0.43) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7466494 | 0.88 | ITGB3 (0.54) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7380577 | 0.87 | CTSL (0.54) | ACECTSLCA12CA1CA2 | |
| SCHEMBL7382271 | 0.87 | ITGB3 (0.48) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7410070 | 0.85 | ITGB3 (0.73) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7410063 | 0.85 | ITGB3 (0.73) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7409522 | 0.85 | ITGB3 (0.73) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7416608 | 0.85 | ITGB3 (0.60) | ITGB3ITGB1ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |