Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP7 | P09237 | 4/20 | 0.65 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | MMP10 | P09238 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410769 | 0.89 | NPY5R (0.61) | MMP7SLC6A9ADAM17MMP10MMP9 | |
| SCHEMBL7408520 | 0.89 | MMP7 (0.53) | MMP7SLC6A9SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7413636 | 0.89 | MMP7 (0.53) | MMP7SLC6A9MMP10MMP9NPY5R | |
| SCHEMBL7417272 | 0.88 | MMP7 (0.53) | MMP7SLC6A9SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7418545 | 0.88 | MMP7 (0.55) | MMP7SLC6A9SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7417008 | 0.88 | MMP7 (0.55) | MMP7SLC6A9SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7419234 | 0.88 | MMP7 (0.53) | MMP7SLC6A9SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7411514 | 0.87 | MMP7 (0.51) | MMP7SLC6A9ADAM17MMP10MMP9 | |
| SCHEMBL7419448 | 0.87 | MMP7 (0.58) | MMP7SLC6A9ADAM17MMP10MMP9 | |
| SCHEMBL7411422 | 0.87 | MMP7 (0.58) | MMP7SLC6A9SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |
| EP-1009737-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999006340-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |