Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.61 |
| ▸ | MMP7 | P09237 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | MMP10 | P09238 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | BMP1 | P13497 | 2/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419448 | 0.90 | MMP7 (0.58) | NPY5RMMP7MMP9MMP10ALDH1A1 | |
| SCHEMBL7413636 | 0.89 | MMP7 (0.53) | NPY5RMMP7MMP9MMP10MMP2 | |
| SCHEMBL7410576 | 0.89 | MMP7 (0.65) | NPY5RMMP7MMP9MMP10ALDH1A1 | |
| SCHEMBL7416850 | 0.89 | MMP7 (0.58) | NPY5RMMP7MMP9MMP10MMP13 | |
| SCHEMBL7411514 | 0.85 | MMP7 (0.51) | NPY5RMMP7MMP9MMP10SLC6A9 | |
| SCHEMBL7411422 | 0.85 | MMP7 (0.58) | NPY5RMMP7MMP9MMP10ALDH1A1 | |
| SCHEMBL7408520 | 0.85 | MMP7 (0.53) | NPY5RMMP7MMP9MMP10MMP2 | |
| SCHEMBL7414985 | 0.85 | MMP7 (0.58) | NPY5RMMP7MMP9MMP10MMP13 | |
| SCHEMBL8006415 | 0.84 | MMP7 (0.70) | MMP7MMP9MMP10MMP13ALDH1A1 | |
| SCHEMBL7416827 | 0.83 | MMP7 (0.51) | NPY5RMMP7MMP9MMP10SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |