Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.54 |
| ▸ | ITGAV | P06756 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | EEF2K | O00418 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878081 | 1.00 | ITGB3 (0.54) | ITGB3ITGAVALDH1A1MAPTKMT2A | |
| SCHEMBL7145763 | 0.94 | ALDH1A1 (0.54) | ITGB3ITGAVALDH1A1MAPTKMT2A | |
| SCHEMBL3837360 | 0.89 | ALDH1A1 (0.54) | ITGB3ITGAVALDH1A1MAPTKMT2A | |
| SCHEMBL7408745 | 0.86 | ITGB3 (0.67) | ITGB3ITGAVALDH1A1ATML3MBTL1 | |
| SCHEMBL3840533 | 0.86 | ALDH1A1 (0.51) | ITGB3ITGAVALDH1A1MAPTKMT2A | |
| SCHEMBL7421213 | 0.85 | ITGB3 (0.61) | ITGB3ITGAVALDH1A1MAPTKMT2A | |
| SCHEMBL5878193 | 0.85 | ITGB3 (0.61) | ITGB3ITGAVALDH1A1MAPTKMT2A | |
| SCHEMBL3834077 | 0.84 | ALDH1A1 (0.50) | ITGB3ITGAVALDH1A1MAPTKMT2A | |
| SCHEMBL6774065 | 0.84 | ALDH1A1 (0.55) | ITGB3ITGAVALDH1A1MAPTKMT2A | |
| SCHEMBL5878110 | 0.83 | ALDH1A1 (0.54) | ITGB3ITGAVALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140809-A1 | NEW BIPHENYL AND BIPHENYL-ANALOGOUS COMPOUNDS AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035864-A1 | NEW BIPHENYL AND BIPHENYL-ANALOGOUS COMPOUNDS AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-22 | — | — | WO | disclosed |