Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615739 | 0.86 | KMT2A (0.54) | RAB9ANPC1MAPTMAPK1HPGD | |
| SCHEMBL6611954 | 0.86 | MAPT (0.63) | RAB9AMAPTMAPK1HPGDCYP1A2 | |
| SCHEMBL7412522 | 0.84 | MAPT (0.48) | RAB9AMAPTMAPK1HPGDCYP3A4 | |
| SCHEMBL21629501 | 0.83 | MAPT (0.56) | RAB9ANPC1MAPTMAPK1HPGD | |
| SCHEMBL30924441 | 0.83 | CYP1A2 (0.55) | RAB9ANPC1MAPTHPGDCYP1A2 | |
| SCHEMBL936440 | 0.82 | MAPT (0.57) | RAB9ANPC1MAPTHPGDCYP1A2 | |
| SCHEMBL16361704 | 0.79 | CYP3A4 (0.50) | RAB9ANPC1MAPTHPGDCYP1A2 | |
| SCHEMBL7411615 | 0.78 | MAPT (0.51) | RAB9ANPC1MAPTMAPK1CYP1A2 | |
| SCHEMBL7411516 | 0.78 | TSHR (0.54) | MAPTMAPK1HPGDCYP1A2CYP2C19 | |
| SCHEMBL7410935 | 0.77 | POLB (0.62) | RAB9ANPC1MAPTMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002088096-A1 | COMPOUNDS INHIBITING CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, PREPARATION AND USES THEREOF | NEURO3D (FR) | 2002-11-07 | — | — | WO | disclosed |