Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409529 | 0.90 | MAPT (0.57) | MAPTMAPK1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL6611954 | 0.86 | MAPT (0.63) | MAPTMAPK1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL7411516 | 0.83 | TSHR (0.54) | MAPTMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7409955 | 0.83 | TSHR (0.42) | MAPTMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6617275 | 0.80 | TSHR (0.53) | MAPTMAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7410935 | 0.80 | POLB (0.62) | MAPTMAPK1NPC1RAB9AKMT2A | |
| SCHEMBL6615739 | 0.80 | KMT2A (0.54) | MAPTMAPK1NPC1RAB9AMEN1 | |
| SCHEMBL18288035 | 0.80 | STS (0.57) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL6612456 | 0.78 | TNFSF11 (0.49) | SMN1; SMN2HTTALDH1A1TNFSF11POLB | |
| SCHEMBL7410864 | 0.78 | RAB9A (0.49) | MAPTMAPK1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002088096-A1 | COMPOUNDS INHIBITING CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, PREPARATION AND USES THEREOF | NEURO3D (FR) | 2002-11-07 | — | — | WO | disclosed |