Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.69 |
| ▸ | CTSL | P07711 | 7/20 | 0.65 |
| ▸ | CTSB | P07858 | 6/20 | 0.61 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | CTSC | P53634 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411039 | 1.00 | CTSS (0.69) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL7411037 | 1.00 | CTSS (0.69) | CTSSCTSLCTSBCTSKCTSH | |
| Hydrochloric Acid SCHEMBL7405419 | 0.88 | CTSS (0.67) | CTSSCTSLCTSBCTSKCTSH | |
| Hydrochloric Acid SCHEMBL7405413 | 0.88 | CTSS (0.67) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL7379870 | 0.85 | CTSS (0.64) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL7414175 | 0.85 | CTSL (0.67) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL7414172 | 0.85 | CTSL (0.67) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL7379872 | 0.85 | CTSS (0.64) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL8691950 | 0.84 | CTSS (0.64) | CTSSCTSLCTSBCTSKCTSH | |
| SCHEMBL8691954 | 0.84 | CTSS (0.64) | CTSSCTSLCTSBCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0817778-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030353-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-10-03 | — | — | WO | disclosed |