Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.37 |
| ▸ | HTR7 | P34969 | 5/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 5/20 | 0.35 |
| ▸ | HTR1B | P28222 | 4/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410893 | 0.89 | HTR1A (0.40) | HTR1AHTR7CHRM3HTR1DHTR1B | |
| SCHEMBL7410902 | 0.85 | HTR1F (0.39) | HTR1AHTR7CHRM3HTR1DHTR1B | |
| SCHEMBL7464791 | 0.81 | HTR1A (0.38) | HTR1AHTR7CHRM3HTR1DHTR1B | |
| SCHEMBL22787309 | 0.80 | TP53 (0.44) | — | |
| SCHEMBL7403668 | 0.78 | CHRM3 (0.47) | HTR1AHTR7CHRM3HTR1DHTR1B | |
| SCHEMBL7411581 | 0.78 | HTR1F (0.36) | HTR1AHTR7CHRM3HTR1DHTR1B | |
| SCHEMBL7405543 | 0.76 | HTR1A (0.47) | HTR1AHTR7CHRM3HTR1DHTR1B | |
| SCHEMBL7412980 | 0.76 | NISCH (0.48) | HTR1AHTR7CHRM3HTR1DHTR1B | |
| SCHEMBL7413012 | 0.74 | TAAR1 (0.50) | HTR1AHTR7CHRM3HTR1DHTR1B | |
| SCHEMBL22787314 | 0.73 | AR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |