Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018555 | 0.90 | KMT2A (0.54) | KMT2AMEN1NPC1RAB9ANOX1 | |
| Hydrochloric Acid SCHEMBL8940098 | 0.89 | KMT2A (0.53) | KMT2AMEN1NPC1RAB9ANOX1 | |
| SCHEMBL6129317 | 0.83 | LMNA (0.48) | KMT2AMEN1NPC1RAB9ANOX1 | |
| SCHEMBL2804456 | 0.79 | SMN1; SMN2 (0.47) | KMT2AMEN1NPC1RAB9ANOX1 | |
| SCHEMBL11851063 | 0.79 | ATG4B (0.55) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11556815 | 0.78 | MEN1 (0.49) | KMT2AMEN1NPC1RAB9ANOX1 | |
| SCHEMBL9125852 | 0.78 | TP53 (0.51) | KMT2AMEN1NPC1RAB9ANOX1 | |
| SCHEMBL397442 | 0.78 | GFER (0.54) | KMT2AMEN1MAPTSMN1; SMN2GAA | |
| SCHEMBL7038319 | 0.78 | MEN1 (0.49) | KMT2AMEN1NPC1RAB9ANOX1 | |
| Hydrochloric Acid SCHEMBL11594933 | 0.77 | GFER (0.53) | KMT2AMEN1MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866705-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0866705-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997014417-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |