Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403870 | 0.87 | PPARG (0.46) | PPARGPPARAL3MBTL1KMT2AACE | |
| SCHEMBL7403869 | 0.87 | PPARG (0.46) | PPARGPPARAL3MBTL1KMT2AACE | |
| SCHEMBL7408782 | 0.87 | PPARG (0.46) | PPARGPPARAL3MBTL1KMT2AACE | |
| SCHEMBL8932405 | 0.79 | PPARG (0.52) | PPARGPPARAALDH1A1LMNAANPEP | |
| SCHEMBL14701896 | 0.76 | PPARG (0.50) | PPARGPPARAALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9813878 | 0.73 | PPARG (0.49) | PPARGPPARAACECTSLCTSS | |
| SCHEMBL14701897 | 0.73 | PPARG (0.45) | PPARGPPARAALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10511874 | 0.73 | PPARG (0.62) | PPARGPPARAALDH1A1LMNAGAA | |
| SCHEMBL13203992 | 0.72 | IDO1 (0.51) | PPARGPPARAALDH1A1LMNAMEN1 | |
| SCHEMBL7870056 | 0.72 | PPARG (0.57) | PPARGPPARAALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720585-A | 2-MERCAPTOPROPANEDIAMINES | E. R. SQUIBB & SONS, INC. | 1988-01-19 | — | — | US | disclosed |