Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14701896 | 0.89 | PPARG (0.50) | PPARGPPARAEPHX1L3MBTL1MEN1 | |
| SCHEMBL14701897 | 0.88 | PPARG (0.45) | PPARGPPARAEPHX1L3MBTL1MEN1 | |
| SCHEMBL10511874 | 0.81 | PPARG (0.62) | PPARGPPARAGAAALDH1A1SYK | |
| SCHEMBL7870056 | 0.80 | PPARG (0.57) | PPARGPPARAEPHX1L3MBTL1GAA | |
| SCHEMBL14974845 | 0.79 | LDHA (0.48) | PPARGPPARAL3MBTL1MEN1NPC1 | |
| SCHEMBL7411635 | 0.79 | PPARG (0.47) | PPARGPPARAEPHX1L3MBTL1MEN1 | |
| SCHEMBL10641625 | 0.78 | GAA (0.51) | PPARGPPARAEPHX1MEN1KMT2A | |
| SCHEMBL7403870 | 0.78 | PPARG (0.46) | PPARGPPARAEPHX1L3MBTL1KMT2A | |
| SCHEMBL7408782 | 0.78 | PPARG (0.46) | PPARGPPARAEPHX1L3MBTL1KMT2A | |
| SCHEMBL7403869 | 0.78 | PPARG (0.46) | PPARGPPARAEPHX1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |
| EP-0144825-B1 | CYCLIC GUANIDINYL THIO CARBAPENEMS | MERCK & CO. INC. (US) | 1989-07-05 | — | — | EP | disclosed |
| US-4717728-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1988-01-05 | — | — | US | disclosed |
| EP-0144825-A1 | Cyclic guanidinyl thio carbapenems | MERCK & CO. INC. (US) | 1985-06-19 | — | — | EP | disclosed |