Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | SDCBP | O00560 | 1/20 | 0.37 |
| ▸ | SDC2 | P34741 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 3/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834577 | 1.00 | MEN1 (0.38) | MEN1KMT2ANPC1RAB9AITGB1 | |
| SCHEMBL3835250 | 1.00 | MEN1 (0.38) | MEN1KMT2ANPC1RAB9AITGB1 | |
| SCHEMBL4600067 | 0.92 | CTRB1 (0.40) | NPC1RAB9AITGB1ITGA4PPARG | |
| SCHEMBL5407004 | 0.92 | CTRB1 (0.40) | NPC1RAB9AITGB1ITGA4PPARG | |
| SCHEMBL4600752 | 0.92 | CTRB1 (0.40) | NPC1RAB9AITGB1ITGA4PPARG | |
| SCHEMBL30510366 | 0.92 | CTRB1 (0.40) | NPC1RAB9AITGB1ITGA4PPARG | |
| SCHEMBL25177964 | 0.90 | ATM (0.39) | MEN1KMT2AITGB1ITGA4ITGB7 | |
| SCHEMBL30767800 | 0.90 | ATM (0.39) | MEN1KMT2AITGB1ITGA4ITGB7 | |
| SCHEMBL5403825 | 0.90 | ITGA4 (0.42) | ITGB1ITGA4ITGB7PPARGPPARA | |
| SCHEMBL7105951 | 0.89 | NPC1 (0.38) | NPC1RAB9AITGB1ITGA4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140809-A1 | NEW BIPHENYL AND BIPHENYL-ANALOGOUS COMPOUNDS AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035864-A1 | NEW BIPHENYL AND BIPHENYL-ANALOGOUS COMPOUNDS AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-22 | — | — | WO | disclosed |