Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541131 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TSHRKDM4EHPGDPOLB | |
| SCHEMBL24201886 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRPOLBLMNABPTF | |
| SCHEMBL25879662 | 0.81 | — | — | |
| SCHEMBL189533 | 0.80 | POLB (0.48) | ALDH1A1TSHRKDM4EHPGDPOLB | |
| SCHEMBL16217245 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TSHRPOLBLMNAGAA | |
| SCHEMBL30707377 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL3716616 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRKDM4EHPGDPOLB | |
| SCHEMBL5327206 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRPOLBLMNABPTF | |
| SCHEMBL1478949 | 0.77 | ALDH1A1 (0.57) | ALDH1A1TSHRPOLBLMNABPTF | |
| SCHEMBL7594583 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319133-A | Isocyanates and their preparation using hypochlorous acid | OLIN CORPORATION (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0107398-B1 | ORTHO SUBSTITUTED DIHYDROXY-2(1H)QUINAZOLINONE-1-ALKANOIC ACIDS | ORTHO PHARMA CORP (US) | 1988-06-08 | — | — | EP | disclosed |
| US-4631283-A | RENAL VASODILATORS, CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
| US-4490374-A | CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0107398-A1 | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4282167-A | IN A WATER INSOLUBLE ORGANIC SOLVENT WITH AN ALKALI METAL HYPOBROMITE | W. R. GRACE & CO. (US) | 1981-08-04 | — | — | US | disclosed |