Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | TDO2 | P48775 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413013 | 1.00 | IDO1 (0.43) | IDO1TDO2HTTTPSAB1KEAP1 | |
| SCHEMBL7384402 | 1.00 | IDO1 (0.43) | IDO1TDO2HTTTPSAB1KEAP1 | |
| SCHEMBL7384409 | 1.00 | IDO1 (0.43) | IDO1TDO2HTTTPSAB1KEAP1 | |
| SCHEMBL7412436 | 1.00 | IDO1 (0.43) | IDO1TDO2HTTTPSAB1KEAP1 | |
| SCHEMBL7412445 | 1.00 | IDO1 (0.43) | IDO1TDO2HTTTPSAB1KEAP1 | |
| SCHEMBL13302789 | 0.93 | IDO1 (0.42) | IDO1TDO2HTTTPSAB1KEAP1 | |
| SCHEMBL7438697 | 0.92 | IDO1 (0.41) | IDO1TDO2HTTTPSAB1KEAP1 | |
| SCHEMBL7521279 | 0.92 | IDO1 (0.41) | IDO1TDO2HTTTPSAB1KEAP1 | |
| SCHEMBL7438694 | 0.92 | IDO1 (0.41) | IDO1TDO2HTTTPSAB1KEAP1 | |
| SCHEMBL7315580 | 0.85 | CTSL (0.46) | IDO1TDO2HTTTPSAB1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175283-A | Enzyme inhibitors for antitrypsin or antithrombin as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-12-29 | — | — | US | claimed |