Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19011137 | 0.82 | HIF1A (0.57) | CES1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL11141085 | 0.74 | SLC6A2 (0.56) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL6438143 | 0.73 | HIF1A (0.55) | CES1SMN1; SMN2HIF1AFAAHSLC6A2 | |
| SCHEMBL1272429 | 0.72 | SMN1; SMN2 (0.64) | CES1SMN1; SMN2HIF1AFAAHSLC6A2 | |
| SCHEMBL2032323 | 0.72 | SMN1; SMN2 (0.64) | CES1SMN1; SMN2HIF1AFAAHSLC6A2 | |
| SCHEMBL1272430 | 0.72 | SMN1; SMN2 (0.64) | CES1SMN1; SMN2HIF1AFAAHSLC6A2 | |
| Acetic Acid SCHEMBL306033 | 0.71 | SLC6A2 (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| Acetic Acid SCHEMBL15865238 | 0.71 | SLC6A2 (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL5709778 | 0.71 | CES1 (1.00) | CES1FAAHCPA1PTPN1 | |
| SCHEMBL9271997 | 0.71 | TAAR1 (0.58) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287605-A1 | AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1988-10-26 | — | — | EP | disclosed |
| WO-1988002363-A1 | AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M (FR) | 1988-04-07 | — | — | WO | disclosed |