SCHEMBL9271997

SCHEMBL9271997

NCC(N)(O)Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.58
SLC6A2 P23975 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.52
HIF1A Q16665 1/20 0.52
CYP1A2 P05177 4/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
FDPS P14324 1/20 0.45
LOXL2 Q9Y4K0 2/20 0.44
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
KIF11 P52732 1/20 0.40
CYP2D6 P10635 3/20 0.39
CYP3A4 P08684 2/20 0.39
PRMT1 Q99873 1/20 0.39
KCNA5 P22460 1/20 0.39
LMNA P02545 1/20 0.39
TSHR P16473 2/20 0.39
RECQL P46063 1/20 0.39
TRPA1 O75762 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL306033 0.90 SLC6A2 (0.53) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
Acetic Acid SCHEMBL15865238 0.90 SLC6A2 (0.53) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL11141085 0.80 SLC6A2 (0.56) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL3747687 0.80 CALM1 (0.52) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL925449 0.79 CYP1A2 (0.52) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL5200141 0.78 SMN1; SMN2 (0.48) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL2778837 0.78 SMN1; SMN2 (0.48) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL8098084 0.78 TAAR1 (0.58) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL135743 0.78 TAAR1 (0.58) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2
SCHEMBL19011137 0.77 HIF1A (0.57) TAAR1SLC6A2SMN1; SMN2HIF1ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4281119-A1 PRECURSOR MARKER AND RADIOTRACER FOR NUCLEAR-MEDICAL DIAGNOSIS AND THERAPY OF BONE-METASTATIC PROSTATE CANCER SCV - SpezialChemikalienVertrieb GmbH (DE) 2023-11-29 EP claimed
US-20230112958-A1 Smart Drug Delivery System and Pharmaceutical Kit for Dual Nuclear Medical Cytotoxic Theranostics SCV-SPEZIALCHEMIKALIENVERTRIEB GMBH (DE) 2023-04-13 US claimed
EP-4076534-A1 SMART DRUG DELIVERY SYSTEM AND PHARMACEUTICAL KIT FOR DUAL NUCLEAR MEDICAL CYTOTOXIC THERANOSTICS SCV - SpezialChemikalienVertrieb GmbH (DE) 2022-10-26 EP claimed
WO-2022157277-A1 PRECURSOR MARKER AND RADIOTRACER FOR NUCLEAR-MEDICAL DIAGNOSIS AND THERAPY OF BONE-METASTATIC PROSTATE CANCER SCV - SpezialChemikalienVertrieb GmbH (DE) 2022-07-28 WO claimed
WO-2021123013-A1 SMART DRUG DELIVERY SYSTEM AND PHARMACEUTICAL KIT FOR DUAL NUCLEAR MEDICAL CYTOTOXIC THERANOSTICS Johannes Gutenberg-Universität Mainz (DE) 2021-06-24 WO claimed
CN-107106711-B Conjugated bisphosphonates for diagnosis and treatment of bone disease SCV公司 2021-06-18 CN claimed
EP-3206720-B1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES SCV GMBH (DE) 2020-04-22 EP claimed
US-20170327520-A1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES SCV GMBH (DE) 2017-11-16 US claimed
CN-107106711-A Conjugation diphosphonate for diagnosing and treating osteopathy SCV公司 2017-08-29 CN claimed
EP-3206720-A1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES SCV GmbH (DE) 2017-08-23 EP claimed
WO-2016058704-A1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES SCV GMBH (DE) 2016-04-21 WO claimed
EP-0442962-B1 LIPOSOMAL RADIOLOGIC CONTRAST AGENTS UNGER EVAN C (US) 1994-01-05 EP claimed
US-20250353833-A1 DPP9 BINDING COMPOUNDS UNIV ANTWERPEN (BE) 2025-11-20 US disclosed
US-20250339566-A1 INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN UNIV ANTWERPEN (BE) 2025-11-06 US disclosed
EP-4531932-A1 INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN Universiteit Antwerpen (BE) 2025-04-09 EP disclosed
WO-2025037000-A1 NOVEL FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND MEDICAL USES THEREOF UNIVERSITEIT ANTWERPEN (BE) 2025-02-20 WO disclosed
WO-2016058704-A1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES SCV GMBH (DE) 2016-04-21 WO disclosed
EP-0670695-A4 POLYMERS AS CONTRAST MEDIA FOR MAGNETIC RESONANCE IMAGING. UNGER EVAN C (US) 1995-12-13 EP disclosed
EP-0670695-A1 POLYMERS AS CONTRAST MEDIA FOR MAGNETIC RESONANCE IMAGING IMARX PHARMACEUTICAL CORP. (US) 1995-09-13 EP disclosed
WO-1994008509-A1 POLYMERS AS CONTRAST MEDIA FOR MAGNETIC RESONANCE IMAGING UNGER EVAN C (US) 1994-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230112958-A1 Smart Drug Delivery System and Pharmaceutical Kit for Dual Nuclear Medical Cytotoxic Theranostics CTSS, CTSV, TK1 TAAR1 755/4885SLC6A2 1216/4885SMN1; SMN2 2089/4885
US-20250339566-A1 INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FIBP, FGF1, FGFR1 TAAR1 4522/4885SLC6A2 3386/4885SMN1; SMN2 3205/4885
US-20170327520-A1 CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES PTH1R, VDR, MEN1 TAAR1 1528/4885SLC6A2 1242/4885SMN1; SMN2 1879/4885
US-20250353833-A1 DPP9 BINDING COMPOUNDS DPP9, DPP7, DPP3 TAAR1 4688/4885SLC6A2 3421/4885SMN1; SMN2 4493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.