SCHEMBL741260

SCHEMBL741260

COc1ccc(S(=O)(=O)c2ccc(OC)c(N=C=O)c2)cc1N=C=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.58
POLB P06746 1/20 0.58
TSHR P16473 1/20 0.58
ALDH1A1 P00352 1/20 0.51
CYP3A4 P08684 1/20 0.51
HPGD P15428 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
PTGS1 P23219 2/20 0.42
PTGS2 P35354 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
PKM P14618 1/20 0.40
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
F2 P00734 3/20 0.38
PRSS1 P07477 3/20 0.38
PRSS2 P07478 3/20 0.38
PRSS3 P35030 3/20 0.38
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5654256 0.86 ALDH1A1 (0.47) MAPK1POLBTSHRALDH1A1CYP3A4
SCHEMBL4244349 0.83 ALDH1A1 (0.45) MAPK1POLBTSHRALDH1A1CYP3A4
SCHEMBL9623531 0.83 POLB (0.41) MAPK1POLBTSHRALDH1A1CYP3A4
SCHEMBL10357296 0.82 ALDH1A1 (0.44) MAPK1POLBTSHRALDH1A1CYP3A4
SCHEMBL9229011 0.82 PTGS2 (0.44) MAPK1POLBTSHRALDH1A1CYP3A4
SCHEMBL5891689 0.79 CYP3A4 (0.73) MAPK1POLBTSHRALDH1A1CYP3A4
SCHEMBL29648847 0.77 CYP3A4 (0.56) MAPK1POLBTSHRALDH1A1CYP3A4
SCHEMBL1019299 0.77 CYP3A4 (0.56) MAPK1POLBTSHRALDH1A1CYP3A4
SCHEMBL29538723 0.77 ALDH1A1 (0.56) ALDH1A1CYP3A4HPGDTDP1SMN1; SMN2
SCHEMBL29510769 0.77 CYP3A4 (0.59) MAPK1POLBTSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767467-B2 Photochromic compound and curable composition containing said photochromic compound TOKUYAMA CORPORATION (JP) 2023-09-26 US disclosed
EP-2970554-B1 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG IND OHIO INC (US) 2023-09-20 EP disclosed
EP-3345954-B1 POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE TOKUYAMA CORP (JP) 2023-07-05 EP disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
EP-3653615-B1 CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION TOKUYAMA CORP (JP) 2023-03-01 EP disclosed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US disclosed
US-11578174-B2 Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane TOKUYAMA CORPORATION (JP) 2023-02-14 US disclosed
US-20220119581-A1 Aircraft Windows PPG INDUSTRIES, INC. 2022-04-21 US disclosed
US-20220056170-A1 OPTICAL MATERIAL COMPOSITION AND OPTICAL MATERIAL TOKUYAMA CORPORATION (JP) 2022-02-24 US disclosed
US-11248083-B2 Aircraft windows PPG INDUSTRIES OHIO, INC. (US) 2022-02-15 US disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 US disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
US-4929707-A Polyurethane base lens resin, plastic lens comprising the resin and preparation method of the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-05-29 US disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329389-A2 Polyurethane base lens and its preparation method MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329386-A2 S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed