SCHEMBL7412848

SCHEMBL7412848

N#Cc1ccc(CCC(N)C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 2/20 0.56
MMP13 P45452 2/20 0.56
GRIK1 P39086 3/20 0.49
GRIK2 Q13002 2/20 0.49
GRIA1 P42261 1/20 0.49
GRIA2 P42262 1/20 0.49
GRIA3 P42263 1/20 0.49
GRIA4 P48058 1/20 0.49
GRIK3 Q13003 1/20 0.49
HTT P42858 1/20 0.45
KCNJ1 P48048 1/20 0.45
KCNH2 Q12809 1/20 0.45
TPH1 P17752 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.44
GRM4 Q14833 1/20 0.44
CTBP2 P56545 1/20 0.44
PRSS1 P07477 1/20 0.43
CTSG P08311 1/20 0.43
CTRB1 P17538 1/20 0.43
CMA1 P23946 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838534 0.83 SLC7A5 (0.62) GRIK1GRIK2KCNH2TPH1DPP4
SCHEMBL43593 0.83 SLC7A5 (0.62) GRIK1GRIK2KCNH2TPH1DPP4
SCHEMBL43594 0.83 SLC7A5 (0.62) GRIK1GRIK2KCNH2TPH1DPP4
SCHEMBL9225716 0.82 MMP12 (0.58) MMP12MMP13HTTKCNJ1KCNH2
SCHEMBL26125750 0.81 GRM4 (0.55) MMP12MMP13GRIK1GRIK2GRIA1
Hydrochloric Acid SCHEMBL10420165 0.81 SLC7A5 (0.61) GRIK1GRIK2KCNH2TPH1DPP4
Hydrochloric Acid SCHEMBL9710930 0.81 SLC7A5 (0.61) GRIK1GRIK2KCNH2TPH1DPP4
Hydrochloric Acid SCHEMBL1183792 0.81 SLC7A5 (0.61) GRIK1GRIK2KCNH2TPH1DPP4
SCHEMBL21447904 0.81 MMP12 (0.61) MMP12MMP13HTTKCNJ1KCNH2
SCHEMBL27864069 0.80 MMP12 (0.56) MMP12MMP13HTTKCNJ1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976635-A1 METHODS OF TREATING HYPERLIPIDEMIA CONDITIONS WITH NETRIN-1 COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-06 EP disclosed
US-5015641-A Dipeptide for vision defects ANDREWS DAVID R (US) 1991-05-14 US disclosed
US-4885293-A CARBOXYALKYL DIPEPTIDES SCHERING CORPORATION (US) 1989-12-05 US disclosed
EP-0195817-B1 CARBOXYALKYLDIPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1989-10-18 EP disclosed
US-4826816-A Antihypertensive compounds SCHERING CORPORATION (US) 1989-05-02 US disclosed
US-4634698-A TOPICAL HYPOTENSIVES SCHERING CORPORATION (US) 1987-01-06 US disclosed
EP-0195817-A1 CARBOXYALKYLDIPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. SCHERING CORP (US) 1986-10-01 EP disclosed
WO-1986001803-A1 CARBOXYALKYLDIPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1986-03-27 WO disclosed
US-4556655-A TREATMENT OF CARDIOVASCULAR DISORDERS AND GLAUCOMA SCHERING CORPORATION (US) 1985-12-03 US disclosed