Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742565 | 0.84 | TSHR (0.41) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28611257 | 0.83 | CYP19A1 (0.41) | KDM4EKMT2ADGKAGPR84TDP1 | |
| SCHEMBL27906115 | 0.82 | TSHR (0.39) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL5477958 | 0.82 | MGAM (0.46) | KMT2ALMNATSHRGPR84CYP3A4 | |
| SCHEMBL873010 | 0.82 | MGAM (0.46) | KMT2ALMNATSHRGPR84CYP3A4 | |
| SCHEMBL5483236 | 0.82 | MGAM (0.46) | KMT2ALMNATSHRGPR84CYP3A4 | |
| SCHEMBL16341246 | 0.80 | MAPT (0.53) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL27576566 | 0.80 | ALDH1A1 (0.40) | MAPTKDM4EDUSP3LMNADGKA | |
| SCHEMBL9174242 | 0.80 | MGAM (0.44) | KMT2ALMNATSHRGPR84CYP3A4 | |
| SCHEMBL29276396 | 0.80 | PRKCA (0.44) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000012466-A1 | FORMAMIDE COMPOUNDS AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |