Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.57 |
| ▸ | HTR1B | P28222 | 3/20 | 0.57 |
| ▸ | HTR1F | P30939 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403551 | 0.90 | HTR1D (0.69) | HTR1DHTR1BHTR1FHTR6CYP1A2 | |
| SCHEMBL7661347 | 0.84 | HTR1F (0.58) | HTR1DHTR1BHTR1FHTR6LMNA | |
| SCHEMBL7407989 | 0.83 | HTR1D (0.55) | HTR1DHTR1BHTR1FHTR6CYP1A2 | |
| Hydrochloric Acid SCHEMBL7405179 | 0.82 | HTR1D (0.54) | HTR1DHTR1BHTR1FHTR6CYP1A2 | |
| SCHEMBL7664459 | 0.80 | HTR1F (0.79) | HTR1DHTR1BHTR1FALOX15MEN1 | |
| SCHEMBL7457595 | 0.80 | KMT2A (0.58) | HTR1DHTR1BHTR1FHSD17B10LMNA | |
| SCHEMBL7407748 | 0.79 | HTR1D (0.51) | HTR1DHTR1BHTR1FHTR6MEN1 | |
| SCHEMBL7415729 | 0.79 | HTR1D (0.51) | HTR1DHTR1BHTR1FHTR6LMNA | |
| SCHEMBL7403681 | 0.79 | HTR1F (0.56) | HTR1DHTR1BHTR1FHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL7406268 | 0.78 | HTR1D (0.50) | HTR1DHTR1BHTR1FHTR6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |