Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 7/20 | 0.51 |
| ▸ | HTR1B | P28222 | 7/20 | 0.51 |
| ▸ | HTR1F | P30939 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RB1 | P06400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407748 | 0.91 | HTR1D (0.51) | HTR1DHTR1BHTR1FHTR6KMT2A | |
| Hydrochloric Acid SCHEMBL7406268 | 0.90 | HTR1D (0.50) | HTR1DHTR1BHTR1FHTR6KMT2A | |
| SCHEMBL7410152 | 0.90 | HTR1D (0.50) | HTR1DHTR1BHTR1FKMT2AMEN1 | |
| SCHEMBL7403681 | 0.86 | HTR1F (0.56) | HTR1DHTR1BHTR1FKMT2ALMNA | |
| SCHEMBL7412246 | 0.86 | HTR1B (0.53) | HTR1DHTR1BKMT2AMEN1EGFR | |
| SCHEMBL7403551 | 0.85 | HTR1D (0.69) | HTR1DHTR1BHTR1FHTR6KMT2A | |
| SCHEMBL7457595 | 0.82 | KMT2A (0.58) | HTR1DHTR1BHTR1FKMT2AMEN1 | |
| SCHEMBL7410598 | 0.81 | HTR1D (0.63) | HTR1DHTR1BHTR1FKMT2AMEN1 | |
| SCHEMBL7407128 | 0.80 | HTR1F (0.67) | HTR1DHTR1BHTR1FHTR6KMT2A | |
| SCHEMBL7412936 | 0.79 | HTR1D (0.57) | HTR1DHTR1BHTR1FHTR6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |