Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 7/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413171 | 1.00 | EPHX1 (0.48) | EPHX1ALOX15ACHECASP2MMP2 | |
| SCHEMBL7194473 | 0.94 | EPHX1 (0.54) | EPHX1CASP2ZDHHC20ZDHHC2EPHX2 | |
| SCHEMBL11574586 | 0.94 | EPHX1 (0.54) | EPHX1CASP2ZDHHC20ZDHHC2EPHX2 | |
| SCHEMBL9803202 | 0.80 | EPHX1 (0.42) | EPHX1ALOX15ACHEMMP2ZDHHC20 | |
| SCHEMBL9803199 | 0.80 | EPHX1 (0.42) | EPHX1ALOX15ACHEMMP2ZDHHC20 | |
| SCHEMBL4222788 | 0.77 | — | — | |
| SCHEMBL4291255 | 0.77 | — | — | |
| SCHEMBL10899308 | 0.76 | ACHE (0.48) | EPHX1ACHE | |
| SCHEMBL28095424 | 0.76 | EPHX1 (0.53) | EPHX1CASP2ZDHHC20ZDHHC2EPHX2 | |
| SCHEMBL11501390 | 0.75 | EPHX1 (0.52) | EPHX1CASP2ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2702035-B1 | PROCESS FOR CONTINUOUS FLOW SYNTHESIS OF BETA-AMINO CROTONATE | COUNCIL SCIENT IND RES (IN) | 2018-03-07 | — | — | EP | claimed |
| US-4902694-A | TREATING CONGESTIVE HEART FAILURE | ELI LILLY AND COMPANY (US) | 1990-02-20 | — | — | US | disclosed |