Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803199 | 1.00 | EPHX1 (0.42) | EPHX1ALOX15EPHX2ACHEMMP2 | |
| SCHEMBL9803208 | 0.89 | MMP1 (0.36) | EPHX1MMP2 | |
| SCHEMBL9803201 | 0.89 | MMP1 (0.36) | EPHX1MMP2 | |
| SCHEMBL7413171 | 0.80 | EPHX1 (0.48) | EPHX1ALOX15EPHX2ACHEMMP2 | |
| SCHEMBL7413162 | 0.80 | EPHX1 (0.48) | EPHX1ALOX15EPHX2ACHEMMP2 | |
| SCHEMBL27786739 | 0.76 | EPHX1 (0.41) | EPHX1ALOX15EPHX2ACHEMMP2 | |
| SCHEMBL11574586 | 0.75 | EPHX1 (0.54) | EPHX1EPHX2ZDHHC20ZDHHC2 | |
| SCHEMBL7194473 | 0.75 | EPHX1 (0.54) | EPHX1EPHX2ZDHHC20ZDHHC2 | |
| SCHEMBL11779060 | 0.74 | SMN1; SMN2 (0.47) | EPHX1EPHX2ZDHHC20ZDHHC2 | |
| SCHEMBL11779067 | 0.74 | SMN1; SMN2 (0.47) | EPHX1EPHX2ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181312-B1 | PROCESS FOR PREPARATION OF SUBSTITUTED PYRIDINES | Monsanto Company (US) | 1991-04-03 | — | — | EP | disclosed |