Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 12/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413164 | 1.00 | EGLN1 (0.36) | EGLN1GCGRMAP4K4KMOTSHR | |
| SCHEMBL7406137 | 0.85 | KMO (0.43) | EGLN1GCGRMAP4K4KMOTSHR | |
| SCHEMBL7406138 | 0.85 | KMO (0.43) | EGLN1GCGRMAP4K4KMOTSHR | |
| SCHEMBL7411451 | 0.81 | HDAC8 (0.43) | EGLN1GCGRMAP4K4HDAC8 | |
| SCHEMBL7412488 | 0.81 | HDAC4 (0.41) | MAP4K4TSHRHDAC8 | |
| SCHEMBL7411447 | 0.81 | HDAC8 (0.43) | EGLN1GCGRMAP4K4HDAC8 | |
| SCHEMBL7412483 | 0.81 | HDAC4 (0.41) | MAP4K4TSHRHDAC8 | |
| SCHEMBL7406546 | 0.77 | TSHR (0.44) | EGLN1MAP4K4TSHR | |
| SCHEMBL7406549 | 0.77 | TSHR (0.44) | EGLN1MAP4K4TSHR | |
| SCHEMBL7407260 | 0.76 | MAP4K4 (0.39) | EGLN1GCGRMAP4K4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999018079-A1 | HETEROARYL BUTYRIC ACIDS AND THEIR DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | WARNER-LAMBERT COMPANY (US) | 1999-04-15 | — | — | WO | claimed |