Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409297 | 0.90 | POLB (0.66) | POLBL3MBTL1DRD4ALDH1A1KDM4E | |
| SCHEMBL7408404 | 0.79 | DRD4 (0.49) | POLBL3MBTL1DRD4ALDH1A1KDM4E | |
| SCHEMBL29876158 | 0.79 | DRD4 (0.61) | POLBL3MBTL1DRD4KDM4EKMT2A | |
| SCHEMBL7413168 | 0.77 | DRD4 (0.59) | POLBL3MBTL1DRD4KDM4EMAPT | |
| SCHEMBL9629591 | 0.75 | DRD4 (0.57) | POLBL3MBTL1DRD4KDM4EKMT2A | |
| SCHEMBL10664492 | 0.75 | DRD4 (0.57) | POLBL3MBTL1DRD4KDM4EMAPT | |
| SCHEMBL7414798 | 0.75 | SHMT2 (0.51) | POLBL3MBTL1DRD4ALDH1A1KDM4E | |
| SCHEMBL10668654 | 0.74 | DRD4 (0.59) | POLBL3MBTL1DRD4KDM4EMAPT | |
| Fumaric Acid SCHEMBL30357950 | 0.73 | MAPT (0.48) | POLBL3MBTL1DRD4ALDH1A1KDM4E | |
| SCHEMBL7409294 | 0.72 | GRM7 (0.53) | POLBL3MBTL1DRD4KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584292-A | Antihypertensive 1,5-benzothiazepine derivatives and compositions thereof | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |