Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417652 | 0.79 | POLB (0.61) | DRD4NOTUMPOLBCYP2D6ALDH1A1 | |
| SCHEMBL7413168 | 0.77 | DRD4 (0.59) | DRD4NOTUMPOLBAVPR2AVPR1A | |
| SCHEMBL29876158 | 0.76 | DRD4 (0.61) | DRD4NOTUMPOLBAVPR2AVPR1A | |
| SCHEMBL10664492 | 0.75 | DRD4 (0.57) | DRD4NOTUMPOLBTP53MAPT | |
| SCHEMBL7409294 | 0.74 | GRM7 (0.53) | DRD4NOTUMPOLBTP53MAPT | |
| SCHEMBL10352868 | 0.74 | NOTUM (0.82) | DRD4NOTUMPOLBCYP2D6AVPR2 | |
| SCHEMBL10668654 | 0.74 | DRD4 (0.59) | DRD4NOTUMPOLBTP53MAPT | |
| SCHEMBL9629591 | 0.72 | DRD4 (0.57) | DRD4NOTUMPOLBTP53MAPT | |
| SCHEMBL7409297 | 0.71 | POLB (0.66) | DRD4POLBALDH1A1TP53MAPT | |
| SCHEMBL10667697 | 0.71 | POLB (0.42) | DRD4POLBTP53MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59104371-A | — | — | None | — | — | JP | disclosed |
| US-4584292-A | Antihypertensive 1,5-benzothiazepine derivatives and compositions thereof | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |
| JP-S59104371-A | 1,5-BENZOTHIAZEPINE DERIVATIVE, HYPOTENSOR CONTAINING IT AS ACTIVE INGREDIENT, AND ITS PREPARATION | KOTOBUKI SEIYAKU KK | 1984-06-16 | — | — | JP | disclosed |