Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.58 |
| ▸ | ESR1 | P03372 | 10/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7411126 | 0.91 | ESR1 (0.62) | F2ESR1ESR2ITGA4 | |
| SCHEMBL7415648 | 0.88 | ESR1 (0.65) | F2ESR1ESR2ITGA4 | |
| SCHEMBL7415915 | 0.86 | ESR1 (0.61) | F2ESR1ESR2ITGA4 | |
| Oxalic Acid SCHEMBL7986025 | 0.84 | F2 (0.62) | F2ESR1ESR2ITGA4 | |
| SCHEMBL6592349 | 0.84 | F2 (0.64) | F2ESR1ESR2ITGA4 | |
| SCHEMBL7414626 | 0.83 | F2 (0.63) | F2ESR1ESR2ITGA4 | |
| Oxalic Acid SCHEMBL7990629 | 0.83 | F2 (0.60) | F2ESR1ESR2ITGA4 | |
| Oxalic Acid SCHEMBL6174272 | 0.82 | F2 (0.57) | F2ESR1ESR2ITGA4 | |
| Oxalic Acid SCHEMBL6593888 | 0.81 | F2 (0.75) | F2ESR1ESR2ITGA4 | |
| Oxalic Acid SCHEMBL7986090 | 0.81 | ITGA4 (0.60) | F2ESR1ESR2ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350774-B1 | Antithrombotic agents | ELI LILLY AND COMPANY | 2002-02-26 | — | — | US | disclosed |