Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.51 |
| ▸ | CTSL | P07711 | 6/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.46 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693018 | 0.92 | CTSK (0.56) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5935001 | 0.92 | CTSK (0.56) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6693027 | 0.92 | CTSK (0.56) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5935088 | 0.87 | CTSK (0.58) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6685164 | 0.87 | CTSK (0.58) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6684776 | 0.86 | CTSK (0.60) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5934876 | 0.86 | CTSK (0.60) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5935098 | 0.86 | CTSK (0.57) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6687789 | 0.86 | CTSK (0.57) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5934875 | 0.84 | CTSK (0.57) | CTSKCTSLCTSBCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |