Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426071 | 0.87 | POLB (0.40) | POLBOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL5860380 | 0.74 | OPRM1 (0.64) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL23094453 | 0.70 | OPRM1 (0.47) | POLBOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL244149 | 0.69 | OPRM1 (0.37) | POLBOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL21874369 | 0.68 | OPRM1 (0.45) | POLBOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL349662 | 0.68 | OPRM1 (0.53) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL30404311 | 0.67 | OPRM1 (0.40) | POLBOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL17796691 | 0.66 | OPRM1 (0.51) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL4984887 | 0.65 | MEN1 (0.53) | POLBOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL28936359 | 0.64 | OPRM1 (0.36) | POLBOPRM1OPRD1OPRK1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | disclosed |