Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680173 | 0.92 | OPRM1 (0.37) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL30680199 | 0.87 | JAK2 (0.42) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL30680201 | 0.82 | MAPT (0.37) | MEN1KMT2A | |
| SCHEMBL29407740 | 0.72 | OPRM1 (0.34) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL13755065 | 0.68 | SLC22A1 (0.39) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL4534061 | 0.68 | OPRM1 (0.42) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL4983144 | 0.67 | MEN1 (0.68) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL472143 | 0.67 | BRD4 (0.39) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL19728884 | 0.65 | SLC22A1 (0.37) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL15070912 | 0.65 | SLC22A1 (0.37) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020957-B | Heterocyclic compounds as MNK inhibitors | 南京天印健华医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |