Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.71 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.64 |
| ▸ | MGAM | O43451 | 3/20 | 0.56 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | SI | P14410 | 3/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779820 | 0.91 | HDAC3 (0.74) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12430571 | 0.90 | HDAC3 (0.73) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6135223 | 0.86 | HDAC3 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4868536 | 0.86 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4953766 | 0.86 | HDAC3 (0.80) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6539230 | 0.86 | HDAC3 (0.80) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2298574 | 0.86 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7317724 | 0.83 | HDAC3 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8827885 | 0.83 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6374055 | 0.83 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |